Proceedings of the International Symposium on Subtypes of Muscarinic Receptors 2 (2nd) Held in Boston, Massachusetts on August 22-24 1985

Partial contents: The molecular basis of receptor selectivity; Biochemical studies on muscarinic receptors in porcine atrium; Muscarinic receptor subclasses: The binding properties of the soluble receptor binding sites; Characteristics of two biochemical responses to stimulation of muscarinic cholin...

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Bibliographic Details
Main Authors: Levine, Ruth R, Birdsall, Nigel J, Giachetti, Antonio, Hammer, Rudolf, Iversen, Leslie L, Jenden, Donald J, North, R A
Format: Report
Language:English
Subjects:
ALZHEIMERS DISEASE
Anatomy and Physiology
AUTORADIOGRAPHY
BINDING SITES
Biochemistry
BRAIN
CELLS(BIOLOGY)
CENTRAL NERVOUS SYSTEM
CHOLINERGIC NERVES
DRUGS
GANGLIA
HEART
HUMANS
ION CHANNELS
ION EXCHANGE
IONIC CURRENT
MEMBRANES(BIOLOGY)
MODULATION
MUCOUS MEMBRANES
MUSCARINE
MUSCARINIC RECEPTORS
MUSCLES
NERVE TRANSMISSION
NERVES
NERVOUS SYSTEM DISEASES
NEUROCHEMICAL TRANSMISSION
PE61102A
PHARMACOLOGICAL ANTAGONISTS
Pharmacology
RECEPTION
RESPONSE(BIOLOGY)
SENSE ORGANS
SIGNALS
SOLUBILITY
STIMULATION(PHYSIOLOGY)
SWINE
SYMPOSIA
SYNAPSE
WU069
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Summary:Partial contents: The molecular basis of receptor selectivity; Biochemical studies on muscarinic receptors in porcine atrium; Muscarinic receptor subclasses: The binding properties of the soluble receptor binding sites; Characteristics of two biochemical responses to stimulation of muscarinic cholinergic receptors; Muscarinic receptors and membrane ion conductances; Muscarinic receptors in the submucous plexus and their roles in mucosal ion transport; A mechanism of muscarinic excitation in dissociated smooth muscle cells; In-vivo labelling of peripheral muscarinic receptors; Modulation of muscarinic receptors and their interactions; The cholinergic hypothesis of dementia; Biochemical and functional basis of putative muscarinic receptor subtypes and its implications; Mapping of subtypes of muscarinic receptors in the human brain with receptor autoradiographic techniques; Inositol lipids and signal transduction at CNS muscarinic receptors; Mechanisms of muscarinic excitatory synaptic transmission in ganglia and brain; Pirenzepine discriminates among ionic responses to acetylcholine in guinea-pig cerebral cortex and reticular nucleus of thalamus. Keywords: Pharmacological antagonists, Binding sites, Alzheimers disease, Drugs, Pharmacological agonists.