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Arachidonic Acid Metabolism in the Nervous System; Physiological and Pathological Significance. Annals of the New York Academy of Science. Volume 5

Arachidonic acid (AA) is an essential polyunsaturated fatty acid that is stored in tissue phospholipids. It serves as a precursor for a variety of products conveniently termed 'the AA cascade' or ' the eicosanoids'. Many of these compounds are biologically active and are composed...

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Bibliographic Details
Main Authors: Barkai, Amiram I, Bazan, Nicholas G
Format: Report
Language:English
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Summary:Arachidonic acid (AA) is an essential polyunsaturated fatty acid that is stored in tissue phospholipids. It serves as a precursor for a variety of products conveniently termed 'the AA cascade' or ' the eicosanoids'. Many of these compounds are biologically active and are composed of prostaglandins, thromboxanes, and leukotrienes. The present volume is a product of an international conference aimed at providing a forum for the review and discussion of recent developments in the research of the neurobiology of AA and its metabolic products, including prostaglandins, thromboxanes, and leukotrienes, in relation to their formation and function in the nervous system. Topics discussed at the conference include: Modulation of Arachidonic Acid Release and Metabolism in the Nervous System; The Arachidonic Acid Cascade in the Nervous System; Arachidonic Acid and Its Metabolites in Signal Transduction; The Role of Cerebral Blood Flow and Arachidonic Acid Metabolism in Brain Injury and Ischemic Damage; Arachidonic Acid Metabolism and Convulsive Disorders; and Arachidonic Acid and its Metabolites in Normal and Abnormal Brain Functions: Sleep Temperature Regulation, Alcohol Effects, and Mental Disorders. Poster Papers are also included.