Assessment of the Genotoxic Potential of Dredged Material

This technical note describes an approach for assessing the genotoxic potential of dredged material. The use of integrated batteries of rapid and mechanistically interpretable in vitro and in vivo assays in a tiered approach is fundamental to applied toxicology. The research described here brings th...

Full description

Saved in:
Bibliographic Details
Main Authors: Honeycutt, Michael E, McFarland, Victor A, Engler, Robert M
Format: Report
Language:English
Subjects:
AQ M00-11-3707
ARMY CORPS OF ENGINEERS
ASSAYING
BIOLOGICAL CONTAMINATION
Civil Engineering
CONTAMINANTS
DNA DAMAGE
DREDGED MATERIALS
DREDGING
ENVIRONMENTAL IMPACT STATEMENTS
GENETICS
GENOTOXIC POTENTIAL
GENOTOXICITY
IN VITRO ANALYSIS
IN VIVO ANALYSIS
RISK ANALYSIS
SEDIMENTS
Solid Wastes Pollution and Control
Test Facilities, Equipment and Methods
TEST METHODS
TOXICITY
Toxicology
WASTE DISPOSAL
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This technical note describes an approach for assessing the genotoxic potential of dredged material. The use of integrated batteries of rapid and mechanistically interpretable in vitro and in vivo assays in a tiered approach is fundamental to applied toxicology. The research described here brings this approach to the testing of sediments. Work completed to date and future work will mesh to form an advanced and cost effective methodology. The purpose of this methodology is to increase the accuracy of environmental risk assessments and facilitate making decisions concerning open-water disposal of dredged material.