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Robust Adaptive Control of Hypnosis During Anesthesia

A closed-loop controller for hypnosis was designed and validated on humans at our laboratory. The controller aims at regulating the Bispectral Index (BIS) - a surrogate measure of hypnosis derived from the electroencephalogram of the patient - with the volatile anesthetic isoflurane administered wit...

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Main Authors:	Grieder, Pascal, Gentilini, Andrea, Morari, Manfred, Schnider, Thomas W
Format:	Report
Language:	English
Subjects:	ADAPTIVE CONTROL SYSTEMS ANESTHESIA ANESTHETICS BIS(BISPECTRAL INDEX) CLOSED LOOP SYSTEMS DIAGNOSTIC EQUIPMENT ELECTROENCEPHALOGRAPHY FOREIGN REPORTS HYPNOSIS IMC(INTERNAL MODEL CONTROLLER) IONS ISOFLURANE MEDICAL RESEARCH Medicine and Medical Research Psychology SWITZERLAND SYMPOSIA
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creator	Grieder, Pascal Gentilini, Andrea Morari, Manfred Schnider, Thomas W
description	A closed-loop controller for hypnosis was designed and validated on humans at our laboratory. The controller aims at regulating the Bispectral Index (BIS) - a surrogate measure of hypnosis derived from the electroencephalogram of the patient - with the volatile anesthetic isoflurane administered with a closed-circuit breathing system. The control algorithm consists of a cascaded Internal Model Controller (IMC) where the master loop aims at regulating BIS. The slave loop tracks endtidal concentration references provided by the master controller. In this paper, a new tuning method is presented. Papers from 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 25-28, 2001, held in Istanbul, Turkey. See also ADM001351 for entire conference on cd-rom.
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The controller aims at regulating the Bispectral Index (BIS) - a surrogate measure of hypnosis derived from the electroencephalogram of the patient - with the volatile anesthetic isoflurane administered with a closed-circuit breathing system. The control algorithm consists of a cascaded Internal Model Controller (IMC) where the master loop aims at regulating BIS. The slave loop tracks endtidal concentration references provided by the master controller. In this paper, a new tuning method is presented. Papers from 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 25-28, 2001, held in Istanbul, Turkey. 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source	DTIC Technical Reports
subjects	ADAPTIVE CONTROL SYSTEMS ANESTHESIA ANESTHETICS BIS(BISPECTRAL INDEX) CLOSED LOOP SYSTEMS DIAGNOSTIC EQUIPMENT ELECTROENCEPHALOGRAPHY FOREIGN REPORTS HYPNOSIS IMC(INTERNAL MODEL CONTROLLER) IONS ISOFLURANE MEDICAL RESEARCH Medicine and Medical Research Psychology SWITZERLAND SYMPOSIA
title	Robust Adaptive Control of Hypnosis During Anesthesia
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