Global Survey of Research and Capabilities in Genetically Engineered Organisms That Could be Used in Biological Warfare or Bioterrorism

This report summarizes the scientific principles underlying genetic modification of microorganisms. It assesses the global availability and cost of technology (know-how, keystone equipment, and synthesized biological materials) needed to acquire and produce potentially lethal biological agents in qu...

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Bibliographic Details
Main Authors: Sagripanti, Jose-Luis, Griffiths, Christine, Ramsbotham, Jr, Alan J
Format: Report
Language:English
Subjects:
BACTERIA
BIODEFENSE
BIOLOGICAL THREAT
BIOLOGICAL WARFARE
BIOSYNTHESIS
BIOTERRORISM
Chemical, Biological and Radiological Warfare
DEOXYRIBONUCLEIC ACIDS
GENETIC ENGINEERING
Genetic Engineering and Molecular Biology
GENETICALLY ENGINEERED ORGANISMS
INFECTIOUS DISEASES
INTERNATIONAL SECURITY
NATIONAL SECURITY
NOVEL ORGANISMS
PATHOGENIC MICROORGANISMS
THREATS
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Summary:This report summarizes the scientific principles underlying genetic modification of microorganisms. It assesses the global availability and cost of technology (know-how, keystone equipment, and synthesized biological materials) needed to acquire and produce potentially lethal biological agents in quantity. The analysis includes technology to engineer novel organisms previously unknown in nature, to synthesize organisms de novo, or to modify naturally pre-existing organisms. The document considers the growing proliferation of legitimate activities, and how such activities may enable nations or non-traditional actors to produce genetically engineered infectious agents for uses that could impact national United States or international security. The original document contains color images. All DTIC reproductions will be in black and white.