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Antibodies to Squalene in US Navy Persian Gulf War Veterans with Chronic Multisymptom Illness

Since the end of the 1991 Gulf War, there have been reports of unexplained, multisymptom illnesses afflicting veterans who consistently report more symptoms than do nondeployed veterans. One of the many possible exposures suspected of causing chronic multisymptom illnesses Gulf War veterans is squal...

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Main Authors:	Phillips, Christopher J, Matyas, Gary R, Hansen, Christian J, Alving, Carl R, Smith, Tyler C, Ryan, Margaret A
Format:	Report
Language:	English
Subjects:	ANTIBODIES DEPLOYMENT Medicine and Medical Research MULTISYMPTOM ILLNESSES NAVAL PERSONNEL OCCUPATIONAL DISEASES PERSIAN GULF WAR REPRINTS SEABEES SIGNS AND SYMPTOMS SQUALENE VACCINES VETERANS(MILITARY PERSONNEL)
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creator	Phillips, Christopher J Matyas, Gary R Hansen, Christian J Alving, Carl R Smith, Tyler C Ryan, Margaret A
description	Since the end of the 1991 Gulf War, there have been reports of unexplained, multisymptom illnesses afflicting veterans who consistently report more symptoms than do nondeployed veterans. One of the many possible exposures suspected of causing chronic multisymptom illnesses Gulf War veterans is squalene, thought to be present in anthrax vaccine. We examined the relationship between squalene antibodies and chronic symptoms reported by Navy construction workers (Seabees), n = 579. 30.2% were deployers, 7.4% were defined as ill, and 43.5% were positive for squalene antibodies. We found no association between squalene antibody status and chronic multisymptom illness (p = 0.465). The etiology of Gulf War syndrome remains unknown, but should not include squalene antibody status. Work unit no. 6002. Published in Vaccine, v27 p3921-3926, 12 June 2009. ISSN 0264-410X
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One of the many possible exposures suspected of causing chronic multisymptom illnesses Gulf War veterans is squalene, thought to be present in anthrax vaccine. We examined the relationship between squalene antibodies and chronic symptoms reported by Navy construction workers (Seabees), n = 579. 30.2% were deployers, 7.4% were defined as ill, and 43.5% were positive for squalene antibodies. We found no association between squalene antibody status and chronic multisymptom illness (p = 0.465). The etiology of Gulf War syndrome remains unknown, but should not include squalene antibody status. Work unit no. 6002. Published in Vaccine, v27 p3921-3926, 12 June 2009. 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subjects	ANTIBODIES DEPLOYMENT Medicine and Medical Research MULTISYMPTOM ILLNESSES NAVAL PERSONNEL OCCUPATIONAL DISEASES PERSIAN GULF WAR REPRINTS SEABEES SIGNS AND SYMPTOMS SQUALENE VACCINES VETERANS(MILITARY PERSONNEL)
title	Antibodies to Squalene in US Navy Persian Gulf War Veterans with Chronic Multisymptom Illness
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