Acute and Four-Week Inhalation Toxicity Study in Rats Exposed to Pyrotechnically Disseminated Black Smoke (PVA)

This study was conducted to evaluate the acute and repeated-dose toxicity of pyrotechnically disseminated black smoke (PVA) when administered by inhalation to male and female rats. Toxicity data in a mammalian system needed to be generated to assess acute and repeated-dose inhalation toxicity health...

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Bibliographic Details
Main Authors: O'Neill, Arthur J, Crouse, Lee C
Format: Report
Language:English
Subjects:
BLACK SMOKE
DOSAGE
EXPOSURE(PHYSIOLOGY)
INHALATION
MAMMALS
MATERIALS
OCCUPATIONAL MEDICINE
PERSONNEL
PYROTECHNICS
SAFETY
SMOKE
TOXICITY
Toxicology
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Summary:This study was conducted to evaluate the acute and repeated-dose toxicity of pyrotechnically disseminated black smoke (PVA) when administered by inhalation to male and female rats. Toxicity data in a mammalian system needed to be generated to assess acute and repeated-dose inhalation toxicity health hazards associated with the material to assure its safety before use by military personnel and to determine an occupational exposure level for workers.