Albuminuria Is an Independent Risk Marker for Mortality and Cardiovascular Morbidity in Patients with Non–ST-segment Elevation Acute Coronary Syndromes: Results from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) Trial

Abstract Background Albuminuria is associated with cardiovascular (CV) outcomes. We evaluated albuminuria, alone and in combination with estimated glomerular filtration rate (eGFR), as a predictor of mortality and CV morbidity in 12,944 patients with non–ST-segment elevation acute coronary syndromes...

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Published in:The American heart journal 2015
Main Authors: Åkerblom, Axel, MD, PhD, Clare, Robert M., MS, Lokhnygina, Yuliya, PhD, Wallentin, Lars, MD, PhD, Held, Claes, MD, PhD, Van de Werf, Frans, MD, Moliterno, David J., MD, Patel, Uptal D., MD, Leonardi, Sergio, MD, MHS, Armstrong, Paul W., MD, Harrington, Robert A., MD, White, Harvey D., DSc, Aylward, Philip E., MD, Mahaffey, Kenneth W., MD, Tricoci, Pierluigi, MD, PhD
Format: Article
Language:English
Subjects:
Cardiovascular
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Summary:Abstract Background Albuminuria is associated with cardiovascular (CV) outcomes. We evaluated albuminuria, alone and in combination with estimated glomerular filtration rate (eGFR), as a predictor of mortality and CV morbidity in 12,944 patients with non–ST-segment elevation acute coronary syndromes (NSTE ACS). Methods Baseline serum creatinine and urinary dipsticks were obtained, with albuminuria stratified into no/trace albuminuria, microalbuminuria (≥30 but
ISSN:0002-8703
DOI:10.1016/j.ahj.2016.04.013