Clinical course and perinatal transmission of chronic hepatitis B during pregnancy in a real-life setting: A prospective cohort study

Summary Objective To determine the clinical course and perinatal transmission of chronic hepatitis B during pregnancy in a real life setting. Methods A total of 221 singleton pregnant women with detectable HBV-DNA levels (≥103 copies/mL) were enrolled during January 2011 to June 2015. Forty-three hi...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of infection 2017
Main Authors: Chen, Zhi-Xian, Gu, Gui-Fang, Bian, Zhao-Lian, Cai, Wei-Hua, Shen, Yi, Hao, Yan-Li, Zhang, Sheng, Shao, Jian-Guo, Qin, Gang
Format: Article
Language:English
Subjects:
Infectious Disease
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Objective To determine the clinical course and perinatal transmission of chronic hepatitis B during pregnancy in a real life setting. Methods A total of 221 singleton pregnant women with detectable HBV-DNA levels (≥103 copies/mL) were enrolled during January 2011 to June 2015. Forty-three high viraemic patients (≥ 106 copies/mL) received telbivudine in the 2nd or 3rd trimester according to their intention, while 89 high viraemic and 79 low viraemic (≥103 and
ISSN:0163-4453
DOI:10.1016/j.jinf.2017.05.012