Standardized Uptake Value on18 F-FDG-PET/CT is a predictor of EGFR T790M mutation status in patients with acquired resistance to EGFR-TKIs

Highlights • We evaluated the association between FDG-PET metrics and EGFR T790 M status. • T790 M status was significantly associated with the levels of SUVmean and SUVmax in FDG-PET/CT. • The survival in patients who acquired T790 M after failure of EGFR-TKIs was significantly longer than those wi...

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Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2016
Main Authors: Yoshida, Tatsuya, Tanaka, Hirotaka, Kuroda, Hiroaki, Shimizu, Junichi, Horio, Yoshitsugu, Sakao, Yukinori, Inaba, Yoshitaka, Iwata, Hiroshi, Hida, Toyoaki, Yatabe, Yasushi
Format: Article
Language:English
Subjects:
Hematology, Oncology and Palliative Medicine
Pulmonary/Respiratory
Online Access:Get full text
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Summary:Highlights • We evaluated the association between FDG-PET metrics and EGFR T790 M status. • T790 M status was significantly associated with the levels of SUVmean and SUVmax in FDG-PET/CT. • The survival in patients who acquired T790 M after failure of EGFR-TKIs was significantly longer than those without T790 M.
ISSN:0169-5002
DOI:10.1016/j.lungcan.2016.07.022