Tamarix gallica phenolics protect IEC-6 cells against H2 O2 induced stress by restricting oxidative injuries and MAPKs signaling pathways

Highlights • H2 O2 induced cytotoxic effect on IEC-6 cells. • T. gallica scavenged H2 O2 and inhibited lipid peroxidation. • T. gallica stopped cell death through JNK dephosphorylation. • T. gallica mitigated oxidative stress and enhanced IEC-6 cell viability.

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Bibliographic Details
Published in:Biomedicine & pharmacotherapy 2017, Vol.89, p.490-498
Main Authors: Bettaib, Jamila, Talarmin, Hélène, Droguet, Mickaël, Magné, Christian, Boulaaba, Mondher, Giroux-metges, Marie-Agnès, Ksouri, Riadh
Format: Article
Language:English
Subjects:
Internal Medicine
Medical Education
Online Access:Get full text
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Description
Summary:Highlights • H2 O2 induced cytotoxic effect on IEC-6 cells. • T. gallica scavenged H2 O2 and inhibited lipid peroxidation. • T. gallica stopped cell death through JNK dephosphorylation. • T. gallica mitigated oxidative stress and enhanced IEC-6 cell viability.
ISSN:0753-3322
DOI:10.1016/j.biopha.2017.02.047