Comparisons of DTI values between controls and MCD patients

Highlights • We investigated diffusion properties of the CC in 32 MCD patients and 32 controls. • Deterministic tractography and ROI-based analyses yielded FA, MD, λ || and λ ⊥. • MCD patients presented significant reductions of FA, increases in MD and λ ⊥. • No differences between MCD subgroups, an...

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Bibliographic Details
Published in:Epilepsy research 2014, Vol.108 (9), p.1533-1542
Main Authors: Andrade, Celi S, Leite, Claudia C, Otaduy, Maria C.G, Lyra, Katarina P, Valente, Kette D.R, Yasuda, Clarissa L, Beltramini, Guilherme C, Beaulieu, Christian, Gross, Donald W
Format: Article
Language:English
Subjects:
Neurology
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Summary:Highlights • We investigated diffusion properties of the CC in 32 MCD patients and 32 controls. • Deterministic tractography and ROI-based analyses yielded FA, MD, λ || and λ ⊥. • MCD patients presented significant reductions of FA, increases in MD and λ ⊥. • No differences between MCD subgroups, and no correlations with clinical parameters. • MCD patients present widespread changes that extend beyond the macroscopic lesions.
ISSN:0920-1211
DOI:10.1016/j.eplepsyres.2014.08.023