Imported severe West Nile virus neuro-invasive disease treated by remdesivir in a patient with anti-CD20 therapy for multiple sclerosis: A case report

West Nile virus (WNV) infection can lead to severe disease, especially in immunocompromised individuals. We report a case of neuroinvasive WNV in a patient receiving ocrelizumab for multiple sclerosis, who recovered after remdesivir and immunoglobulin treatment. This case highlights the diagnostic a...

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Bibliographic Details
Published in:CMI Communications 2024-12, Vol.1 (2), Article 105034
Main Authors: Shamsher, Ehtesham, Dash, Jonathan, Serratrice, Jacques, Coen, Matteo, Zacharias-Fontanet, Aurélie, Laubscher, Florian, Schibler, Manuel, Uginet, Marjolaine, Vetter, Pauline
Format: Article
Language:English
Subjects:
Immunosuppression
Multiple sclerosis
Ocrelizumab
Remdesivir
West Nile virus
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Summary:West Nile virus (WNV) infection can lead to severe disease, especially in immunocompromised individuals. We report a case of neuroinvasive WNV in a patient receiving ocrelizumab for multiple sclerosis, who recovered after remdesivir and immunoglobulin treatment. This case highlights the diagnostic and therapeutic challenges regarding neuroinvasive WNV infection in immunocompromised patients.
ISSN:2950-5909
2950-5909
DOI:10.1016/j.cmicom.2024.105034