Effect of pulmonary artery catheter, type & combination of vasoactives for optimizing lactate clearance in acute myocardial infarction complicated by cardiogenic shock

Lactate clearance(LC) is critical in managing critically ill patients. We hypothesized that treatment allocation with different vasoactive drugs or the presence of a pulmonary artery catheter (PAC) could affect the behavior of lactate dynamics and, ultimately, the mortality in AMI-CS. In 651 patient...

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Published in:Journal of critical care 2025-04, Vol.86, Article 154990
Main Authors: Ortega-Hernández, Jorge A., González-Pacheco, Héctor, García-Ruiz, Mauricio, Manzur-Sandoval, Daniel, Gopar-Nieto, Rodrigo, Sierra-Lara-Martínez, Daniel, Araiza-Garaygordobil, Diego, Mendoza-García, Salvador, Arzate-Ramírez, Arturo, Montañez-Orozco, Álvaro, Baeza-Herrera, Luis Augusto, Altamirano-Castillo, Alfredo, Valdespino Trejo, Adrian Aquiles, Hernández-Montfort, Jaime, Arias-Mendoza, Alexandra
Format: Article
Language:English
Subjects:
Acute myocardial infarction
Cardiogenic shock
Lactate clearance
Mortality
Survival analysis
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Summary:Lactate clearance(LC) is critical in managing critically ill patients. We hypothesized that treatment allocation with different vasoactive drugs or the presence of a pulmonary artery catheter (PAC) could affect the behavior of lactate dynamics and, ultimately, the mortality in AMI-CS. In 651 patients with AMI-CS, we examined the relationship of LC time with clinical, laboratory, and CS-management variables. Complete LC time was defined as serum lactate levels less than
ISSN:0883-9441
DOI:10.1016/j.jcrc.2024.154990