Effects of prenatal multiple micronutrient supplementation on growth and cognition through 2 y of age in rural Bangladesh: the JiVitA-3 Trial12

Background: Childhood undernutrition may have prenatal origins, and the impact of prenatal interventions on postnatal growth is not well known. Objective: We assessed the effects of prenatal multiple micronutrient (MM) supplementation on child growth and cognitive development. Design: In a cluster-r...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2016-10, Vol.104 (4), p.1175-1182
Main Authors: Christian, Parul, Kim, Jeongyong, Mehra, Sucheta, Shaikh, Saijuddin, Ali, Hasmot, Shamim, Abu Ahmed, Wu, Lee, Klemm, Rolf, Labrique, Alain B, West, Keith P
Format: Article
Language:English
Subjects:
children
cognition
growth
micronutrients
prenatal
stunting
Online Access:Get full text
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Summary:Background: Childhood undernutrition may have prenatal origins, and the impact of prenatal interventions on postnatal growth is not well known. Objective: We assessed the effects of prenatal multiple micronutrient (MM) supplementation on child growth and cognitive development. Design: In a cluster-randomized controlled trial in rural Bangladesh, prenatal MM supplementation compared with iron-folic acid (IFA) supplementation was examined for its impact on growth assessed longitudinally from birth up to 24 mo of age (n = 8529) and, in a subsample (n = 734), on cognitive function at 24 mo of age by use of the Bayley scales of infant and toddler development–third edition test. Results: Prevalence of stunting at birth [length for age z score (LAZ):
ISSN:0002-9165
1938-3207
DOI:10.3945/ajcn.116.135178