Hypercholesterolemia in renal transplant recipients : contributing factors, effect of dietary modification and fluvastatin therapy

Hypercholesterolemia which frequently follows renal transplantation, places kidney graft recipients at an increased risk for atherosclerosis and cardiovascular diseases. We attempt in this study to determine the prevalence, and evaluate severity and treatment of hypercholesterolemia in kidney transp...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 1999-04, Vol.10 (2), p.148-151
Main Authors: Rashid, Awwad, Taha, Mustafa, Badawi, Usamah, Hamid, Ahmad, al-Sayyid, Muhammad, Abbud, Umar Ibrahim, Ashur, Adil M.
Format: Article
Language:English
Subjects:
Hypercholesteremia
Kidneys
Transplantation
الدم
العلاج الغذائي
الكلى
الكوليسترول
الليبيدات
المضاعفات
زرع الأعضاء
علم المداواة
فرط كوليسترول الدم
مواد مضادة للكوليسترول
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Summary:Hypercholesterolemia which frequently follows renal transplantation, places kidney graft recipients at an increased risk for atherosclerosis and cardiovascular diseases. We attempt in this study to determine the prevalence, and evaluate severity and treatment of hypercholesterolemia in kidney transplant recipients. We studied 78 renal transplant patients with a mean age of 42.1 years and mean transplant duration of 6.2 years (range from six months to 8.5 years). They were on triple immunosuppressive therapy and had serum creatinine level of less than 160µmol/L. Thirty-one patients (39.8%) were found to have blood cholesterol levels > 6.4 mmol/L. Significant positive correlation was found between hypercholesterolemia and cyclosporine blood levels above 200 ng/ml (p
ISSN:1319-2442
2320-3838