Renal transplant in a tuberous sclerosis patient with bilateral giant renal angiomyolipomas and concurrent renal carcinoma

• Published in: Saudi journal of kidney diseases and transplantation 2013-03, Vol.24 (2), p.318-321
• Main Authors: Naqvi, Sayyid A. A. Anwar, Asif, Muhammad, Salihi, Mirza Ali, Yunus, Mahirah, Ahmad, Ijaz, Sultan, Jawhar, Mubarak, Muhammad, Husayn, Mansur, Rizvi, Sayyid A. H.
• Format: Article
• Language: English
• Subjects: Adult; Angiomyolipoma - diagnosis; Angiomyolipoma - etiology; Angiomyolipoma - surgery; Cancer; Carcinoma, Renal cell; Carcinoma, Renal Cell - diagnosis; Carcinoma, Renal Cell - etiology; Carcinoma, Renal Cell - surgery; Care and treatment; Case studies; Diagnosis; Diseases; Female; Humans; Kidney Neoplasms - diagnosis; Kidney Neoplasms - etiology; Kidney Neoplasms - surgery; Kidney Transplantation; Kidneys; Living Donors; Neoplasms, Complex and Mixed - diagnosis; Neoplasms, Complex and Mixed - etiology; Neoplasms, Complex and Mixed - surgery; Nephrectomy; Organ transplant recipients; Patient outcomes; Prognosis; Risk factors; Tomography, X-Ray Computed; Transplantation; Treatment Outcome; Tuberous sclerosis; Tuberous Sclerosis - complications; Tuberous Sclerosis - diagnosis; Tuberous Sclerosis - surgery; الأمراض الوراثية; الأورام الشحمية العضلية الوعائية; السرطان; القصور العقلي; الكلى; المرضى; زرع الأعضاء
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.109591

Co-existence of angiomyolipoma (AML) and renal cell carcinoma (RCC) in the same tumor mass is very rare and only eight cases have been reported. We present a case of a young female with tuberous sclerosis complex (TSC) with bilateral huge renal AMLs. Both tumors were removed, one of which revealed co-incidental RCC. She was subsequently successfully transplanted a kidney from her brother and is maintaining normal graft function eight months post-transplant. No recurrence or metastases of RCC has been detected till the last follow-up.