Hyperuricosuria, an often overlooked cause of recurrent oliguria in children

The association of oliguria with hyperuricosuria is often overlooked. Herein, we report an infant who since the age of five months had recurrent oliguria secondary to hyperuricosuria documented several times in the hospital. The decreased urine output co­incided with the presence of increased excret...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2008-07, Vol.19 (4), p.619-623
Main Author: Aql, Kamal
Format: Article
Language:English
Subjects:
Alkyl and Aryl Transferases
Allopurinol - therapeutic use
Child, Preschool
Female
Humans
Hyperuricosuria
Oliguria
Oliguria - etiology
Oxidases
Pediatric urology
Recurrent oliguria
Treatment Outcome
Uric acid
Uric Acid - blood
Urination disorders
Urologic Diseases - complications
Urologic Diseases - drug therapy
الأطفال
البول الدموي
التشخيص
حمض اليوريك
علم الأمراض
فرط حمض يوريك الدم
قلة البول
مسببات الأمراض
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Summary:The association of oliguria with hyperuricosuria is often overlooked. Herein, we report an infant who since the age of five months had recurrent oliguria secondary to hyperuricosuria documented several times in the hospital. The decreased urine output co­incided with the presence of increased excretion of uric acid, which fluctuated within 24 hours as well as every few weeks. The child responded to treatment with increase in the fluid fluid intake along with the xanthine oxidase inhibitor, allopurinol. Being alert for hyperuricosuria in cases of oliguria, especially if there is history of gout or stones, may avoid performing many unnecessary investigations.
ISSN:1319-2442
2320-3838