Cerebral salt wasting in a patient with head trauma : management with saline hydration and fludrocortison

Hyponatremia secondary to the syndrome of inappropriate anti-diuretic hormone secretion is commonly observed in patients with various neurological disorders. Cerebral salt wasting (CSW), although uncommon, has also been reported to frequently result in hyponatremia. Here, we report a case of CSW in...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2007, Vol.18 (1), p.95-99
Main Authors: Askar, Akram, Tarif, Numan
Format: Article
Language:English
Subjects:
Complications
Head
Hyponatremia
Wounds and injuries
الجروح و الإصابات
الرأس
المرضى
المضاعفات
نقص صوديوم الدم
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Summary:Hyponatremia secondary to the syndrome of inappropriate anti-diuretic hormone secretion is commonly observed in patients with various neurological disorders. Cerebral salt wasting (CSW), although uncommon, has also been reported to frequently result in hyponatremia. Here, we report a case of CSW in a patient with head trauma without evidence of cerebrovascular injury or brain edema. He was diagnosed on the basis of high fractional excretion of urinary sodium and uric acid along with extremely low serum uric acid. Improvements in serum sodium levels after saline hydration and fludrocortisone administration further supported the diagnosis, even in the presence of normal brain and atrial natriuretic peptide levels.
ISSN:1319-2442
2320-3838