Preparation and Characterization of Magnetic Mesoporous Bioactive Glass/Carbon Composite Scaffolds

The magnetic Fe-MBG/C composite scaffolds with enhanced mechanical strength and multifunctionality have been successfully prepared. The study showed that the Fe-MBG/C composite scaffolds with the porosity of ca. 80% had interconnected macropores (200–500 µm) and mesopores (3.7–4.4 nm) and significan...

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Published in:Journal of chemistry 2013, Vol.2013 (2013), p.1-11
Main Authors: Zhang, Jianhua, Zhu, Min, Zhou, Yinghong, Liu, Yunfei, He, Xing, Tao, Cuilian, Zhu, Yufang
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container_issue 2013
container_start_page 1
container_title Journal of chemistry
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creator Zhang, Jianhua
Zhu, Min
Zhou, Yinghong
Liu, Yunfei
He, Xing
Tao, Cuilian
Zhu, Yufang
description The magnetic Fe-MBG/C composite scaffolds with enhanced mechanical strength and multifunctionality have been successfully prepared. The study showed that the Fe-MBG/C composite scaffolds with the porosity of ca. 80% had interconnected macropores (200–500 µm) and mesopores (3.7–4.4 nm) and significantly enhanced the compressive strength compared to the pure MBG scaffolds. Importantly, the Fe-MBG/C composite scaffolds exhibited good bioactivity and sustained drug release property. At the same time, the Fe-MBG/C composite scaffolds could generate heat to raise the temperature of surrounding environment in an alternating magnetic field due to their superparamagnetic behavior. Therefore, the magnetic Fe-MBG/C composite scaffolds could form a multifunctional platform with bone regeneration, magnetic hyperthermia, and local drug delivery and have more potential for use in the regeneration of the critical-sized bone defects caused by bone tumors.
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title Preparation and Characterization of Magnetic Mesoporous Bioactive Glass/Carbon Composite Scaffolds
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