Sustained remission in a case of lupus nephritis with cyclosporin therapy

Systemic lupus erythematosus (SLE) in severe form still presents a major therapeutic challenge. Aggressive treatment of severe renal lesions has improved the prognosis of renal disease over the last decade. However, this benefit is quite frequently offset by the side effects and toxicity of the trea...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2001-10, Vol.12 (4), p.525-529
Main Authors: Rabbani, Malik Anas, Ahmad, Asim, Shah, Sayyid Mansur Ahmad
Format: Article
Language:English
Subjects:
Cyclosporin A
Cyclosporine
Lupus nephritis
Systemic lupus erythematosus
التهاب الكلى الذئبي
المرضى
علم المداواة
عوامل مثبطة للمناعة
مآلات المرض
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Summary:Systemic lupus erythematosus (SLE) in severe form still presents a major therapeutic challenge. Aggressive treatment of severe renal lesions has improved the prognosis of renal disease over the last decade. However, this benefit is quite frequently offset by the side effects and toxicity of the treatment. Moreover, the disease may appear to be poorly responsive to treatment with steroids and cytotoxic drugs. We report a case of lupus nephritis that relapsed despite having adequate steroid and cytotoxic therapy, but later was successfully treated with cyclosporin. Fifteen months after discontinuing the treatment with cyclosporin, the patient continued to remain in remission.
ISSN:1319-2442
2320-3838