Biodegradation of phosphonomycin by Rhizobium huakuii PMY1

The biodegradation by Rhizobium huakuii PMY1 of up to 10 mM phosphonomycin as a carbon, energy, and phosphorus source with accompanying Pi release is described. This biodegradation represents a further mechanism of resistance to this antibiotic and a novel, phosphate-deregulated route for organophos...

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Bibliographic Details
Published in:Applied and Environmental Microbiology 1998-01, Vol.64 (1), p.356-358
Main Authors: McGrath, J.W, Hammerschmidt, F, Quinn, J.P
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - metabolism
Anti-Bacterial Agents - pharmacology
ANTIBIOTICOS
ANTIBIOTICS
ANTIBIOTIQUE
Bacteria
BIODEGRADACION
BIODEGRADATION
Biodegradation, Environmental
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
Carbon - metabolism
Drug Resistance, Microbial
Fosfomycin - chemistry
Fosfomycin - metabolism
Fosfomycin - pharmacology
Fundamental and applied biological sciences. Psychology
General Microbial Ecology
Metabolism
Microbiology
Mission oriented research
Molecular Structure
Phosphorus - metabolism
Physiology and metabolism
RHIZOBIUM
Rhizobium - drug effects
Rhizobium - metabolism
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Summary:The biodegradation by Rhizobium huakuii PMY1 of up to 10 mM phosphonomycin as a carbon, energy, and phosphorus source with accompanying Pi release is described. This biodegradation represents a further mechanism of resistance to this antibiotic and a novel, phosphate-deregulated route for organophosphonate metabolism by Rhizobium spp
ISSN:0099-2240
1098-5336
DOI:10.1128/aem.64.1.356-358.1998