Nutritional intervention with omega-3 fatty acids in a case of malignant fibrous histiocytoma of the lungs

We present a case of a 78-yr-old man with malignant fibrous histiocytoma with multiple lesions in both lungs. Following diagnosis, he declined conventional chemotherapy and elected nutritional intervention by increasing intake of omega-3 fatty acids and lowering intake of omega-6 fatty acids. We est...

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Bibliographic Details
Published in:Nutrition and cancer 2005-01, Vol.52 (2), p.121-129
Main Authors: Pardini, R.S, Wilson, D, Schiff, S, Bajo, S.A, Pierce, R
Format: Article
Language:English
Subjects:
Aged
algae and seaweeds
algae oils
anticarcinogenic activity
antioxidant activity
Biological and medical sciences
clinical nutrition
Disease Progression
docosahexaenoic acid
Docosahexaenoic Acids - therapeutic use
dose response
eicosapentaenoic acid
Eicosapentaenoic Acid - therapeutic use
elderly
Epidemiology
fat intake
Fatty Acids, Omega-3 - therapeutic use
Fish Oils
Histiocytoma, Malignant Fibrous - diet therapy
Histiocytoma, Malignant Fibrous - pathology
histiocytosis
Humans
lung neoplasms
Lung Neoplasms - diet therapy
Lung Neoplasms - pathology
Male
Medical sciences
nutritional intervention
omega-3 fatty acids
Other treatments
patients
sarcoma
symptoms
Treatment. General aspects
Tumors
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Summary:We present a case of a 78-yr-old man with malignant fibrous histiocytoma with multiple lesions in both lungs. Following diagnosis, he declined conventional chemotherapy and elected nutritional intervention by increasing intake of omega-3 fatty acids and lowering intake of omega-6 fatty acids. We estimated that he consumed 15 g of the long-chain omega-3 fatty acids eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) per day, and the ratio of linoleic acid/long-chain omega-3 fatty acids in his diet was 0.81. Serial computed tomography scans and pulmonary x-rays revealed remarkably a slow and steady decrease in the size and number of bilateral nodules. He has no apparent side effects from consuming large quantities of fish and algae oils rich in DHA and EPA and he remains asymptomatic.
ISSN:0163-5581
1532-7914
DOI:10.1207/s15327914nc5202_2