Molecular Characterization of Cryptosporidium spp. from Children in Kolkata, India

The intracellular parasite Cryptosporidium is responsible for severe diarrhea in immunocompromised persons in developing countries. Few studies on the characterization of the parasite in India are available. In this study, molecular characterization of the parasite from diarrheic children was carrie...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2006-11, Vol.44 (11), p.4246-4249
Main Authors: Das, Pradeep, Roy, Seuli Saha, MitraDhar, Kakali, Dutta, Phalguni, Bhattacharya, Mihir K, Sen, Abhik, Ganguly, Sandipan, Bhattacharya, Sujit K, Lal, Altaf A, Xiao, Lihua
Format: Article
Language:English
Subjects:
Age Factors
Animals
Base Sequence
Biological and medical sciences
Child, Preschool
Cryptosporidiosis - transmission
Cryptosporidium
Cryptosporidium - classification
Cryptosporidium - genetics
Diarrhea - parasitology
Fundamental and applied biological sciences. Psychology
Genotype
Humans
Infant
Infant, Newborn
Infectious diseases
Medical sciences
Microbiology
Molecular Sequence Data
Parasitology
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
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Summary:The intracellular parasite Cryptosporidium is responsible for severe diarrhea in immunocompromised persons in developing countries. Few studies on the characterization of the parasite in India are available. In this study, molecular characterization of the parasite from diarrheic children was carried out by PCR-restriction fragment length polymorphism analysis. At least three genotypes were identified. Out of 40 positive samples, 35 were positive for C. hominis, 4 were positive for C. parvum, and 1 was positive for C. felis. This study clearly suggests that cryptosporidiosis in this region is caused largely by anthroponotic transmission.
ISSN:0095-1137
1098-660X
1098-5530
DOI:10.1128/JCM.00091-06