IgY – Immune component of eggs as a source of passive immunity for animals and humans

Antibodies deposited in the avian egg have been found to be a platform for the production of a diverse array of safe commercial products for improving animal health and the efficiency of their production. This review provides over 20 years of experience and comments on the production, storage, stabi...

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Bibliographic Details
Published in:World's poultry science journal 2010-06, Vol.66 (2), p.215-226
Main Authors: COOK, M.E., TROTT, D.L.
Format: Article
Language:English
Subjects:
alternative egg product
antibodies
avian immunoglobulin
chickens
egg antibody
eggs
Feed additives
IgY
immune component
immune system
immunoglobulin Y
immunoglobulins
literature reviews
non-traditional egg product
ova
passive immunity
protective effect
storage conditions
storage quality
vaccination
vaccine development
vaccines
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Summary:Antibodies deposited in the avian egg have been found to be a platform for the production of a diverse array of safe commercial products for improving animal health and the efficiency of their production. This review provides over 20 years of experience and comments on the production, storage, stabilisation and use of egg yolk antibodies. Host targeted immuno-therapies presented in this review provides the reader with new areas of research and discovery. Standards for vaccination protocols, methods of isolating and storing the antibodies are also presented. Areas needing to advance the commercial use of egg antibodies, including methods to improve antibody titre, methods to heat stabilise the antibody molecule, and the identification of new uses and targets are also discussed. Examples of successful uses of egg antibodies as feed additives are also presented.
ISSN:0043-9339
1743-4777
DOI:10.1017/S0043933910000279