solution structure of the Leu22 leads to Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity

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Bibliographic Details
Published in:Journal of molecular biology 1998, Vol.277 (3), p.621-634
Main Authors: Starich, M.R, Wikstrom, M, Schumacher, S, Arst, H.N. Jr, Gronenborn, A.M, Clore, G.M
Format: Article
Language:English
Subjects:
Aspergillus nidulellus
binding
DNA
DNA-binding domains
DNA-binding proteins
leucine
molecular conformation
mutants
nuclear magnetic resonance spectroscopy
pdb/6gat
pdb/6gatmr
pdb/7gat
transcription (genetics)
valine
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ISSN:0022-2836
1089-8638