Evaluation of hematological changes in population exposed to fluoride

Absorption of fluorine compounds produces chronic toxicity and the hematological changes appear earlier in blood than other organs. A study was undertaken to determine the status of hematological changes in the individual residing in fluoride-contaminated area. Two hundred and fifty nine and 233 sub...

Full description

Saved in:
Bibliographic Details
Published in:Toxicological and environmental chemistry 2012-12, Vol.94 (10), p.2052-2056
Main Authors: Ravichandran, B, Chattopadhyay, S, Gangopadhyay, P.K, Saiyed, H.N
Format: Article
Language:English
Subjects:
absorption
at-risk population
Blood
chronic toxicity
Counting
Erythrocytes
Exposure
fluorides - hematology Hb
Fluorine
Fluorine compounds
health status
Hematology
Hemoglobin
Human exposure
Leukocytes
Organs
RBC
Toxicity
Toxicology
WBC
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Absorption of fluorine compounds produces chronic toxicity and the hematological changes appear earlier in blood than other organs. A study was undertaken to determine the status of hematological changes in the individual residing in fluoride-contaminated area. Two hundred and fifty nine and 233 subjects from the contaminated area and an unaffected area, respectively, were selected for hematological investigations. Total erythrocytes (red blood corpuscles (RBC)), total leucocytes (white blood corpuscles (WBC)), and hemoglobin (Hb) concentrations were determined in these populations. Results revealed that Hb values were significantly lower among all age groups in the exposed population compared to control subjects. There was a quantitative rise in WBC counts in study subjects compared to controls. The RBC counts showed reduction among exposed population.
ISSN:1029-0486
0277-2248
1029-0486
DOI:10.1080/02772248.2012.723485