Plasmodium knowlesi: A Malaria Parasite of Monkeys and Humans

Plasmodium knowlesi is a malaria parasite of monkeys of Southeast Asia that is transmitted by mosquitoes of the Anopheles leucosphyrus group. Humans are frequently infected with this parasite and misdiagnosed as being infected with Plasmodium malariae . The parasite was a major monkey animal model f...

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Bibliographic Details
Published in:Annual review of entomology 2012-01, Vol.57 (1), p.107-121
Main Author: Collins, William E
Format: Article
Language:English
Subjects:
animal models
Animals
Anopheles
Anopheles leucosphyrus
Biological and medical sciences
Borneo
Fundamental and applied biological sciences. Psychology
genome
Haplorhini - parasitology
Host-Parasite Interactions
human malaria
Human protozoal diseases
Humans
Infectious diseases
Insect Vectors - parasitology
Insecta
Invertebrates
Malaria
Malaria - immunology
Malaria - parasitology
Malaria - transmission
Mammalia
Medical sciences
Monkey Diseases - parasitology
monkeys
mosquitoes
parasites
Parasitic diseases
Plasmodium knowlesi
Plasmodium knowlesi - physiology
Plasmodium malariae
Protozoal diseases
Southeast Asia
vaccines
Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution
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Summary:Plasmodium knowlesi is a malaria parasite of monkeys of Southeast Asia that is transmitted by mosquitoes of the Anopheles leucosphyrus group. Humans are frequently infected with this parasite and misdiagnosed as being infected with Plasmodium malariae . The parasite was a major monkey animal model for developing antimalarial vaccines and investigations of the biology of parasite invasion. P. knowlesi is the first monkey malaria parasite genome to be sequenced and annotated.
ISSN:0066-4170
1545-4487
DOI:10.1146/annurev-ento-121510-133540