New Monoacylglycerol and Antimicrobial Constituents from the Stem Barks of Berlinia confusa

Phytochemical examination of Berlinia confusa led to the isolation of a monoacylglyceride named 1-O-tetracosaenoyl-sn-1-glycerol (1) as well as two other compounds: sitosteryl-β-D-glucoside (2) and betulinic acid (3) from the dried stem bark of B. confusa. The structure of the new compound was eluci...

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Bibliographic Details
Published in:Journal of herbs, spices & medicinal plants spices & medicinal plants, 2012-04, Vol.18 (2), p.111-131
Main Authors: Lasisi, Adebayo A, Adesomoju, Akinbo A
Format: Article
Language:English
Subjects:
1-O-tetracosaenoyl-sn-1-glycerol
bark
Berlinia
betulinic acid
Biological and medical sciences
Chemical compounds
Flowers & plants
General pharmacology
Gram-negative bacteria
leguminosae
Medical sciences
microorganisms
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytochemicals
spectroscopy
Spectrum analysis
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Summary:Phytochemical examination of Berlinia confusa led to the isolation of a monoacylglyceride named 1-O-tetracosaenoyl-sn-1-glycerol (1) as well as two other compounds: sitosteryl-β-D-glucoside (2) and betulinic acid (3) from the dried stem bark of B. confusa. The structure of the new compound was elucidated on the basis of spectroscopic studies and comparison with known related compounds. The extracts and the isolated compounds displayed inhibitory activities against selected gram-positive and gram-negative microorganisms with diameter zone of inhibition values of 15.1 ± 0.3 to 6.0 ± 0.4 mm.
ISSN:1540-3580
1049-6475
1540-3580
DOI:10.1080/10496475.2011.645269