Experimental study on antinociceptive and anti-allergy effects of patchouli oil

Pogostemon cablin (Blanco) Benth. (Lamiaceae), which is named ‘Guang-Huo-Xiang’ in Chinese, has various therapeutic functions to remove dampness, relieve summer-heat and exterior syndrome, stop vomiting, and stimulate appetite. Patchouli oil is the essential oil of Pogostemonis herba. This study is...

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Bibliographic Details
Published in:The Journal of essential oil research 2013-12, Vol.25 (6), p.488-496
Main Authors: He, Jing-Jin, Chen, Hai-Ming, Li, Chu-Wen, Wu, Dian-Wei, Wu, Xiao-Li, Shi, Shu-Jiang, Li, Yu-Cui, Chen, Jian-Nan, Su, Zi-Ren, Lai, Xiao-Ping
Format: Article
Language:English
Subjects:
analgesic effect
anaphylaxis
anti-allergy activity
antinociceptive activity
appetite
blood serum
delayed hypersensitivity
essential oils
frequency
latent period
mice
oils
patchouli oil
Pogostemon cablin
rats
vomiting
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Summary:Pogostemon cablin (Blanco) Benth. (Lamiaceae), which is named ‘Guang-Huo-Xiang’ in Chinese, has various therapeutic functions to remove dampness, relieve summer-heat and exterior syndrome, stop vomiting, and stimulate appetite. Patchouli oil is the essential oil of Pogostemonis herba. This study is aimed to investigate the antinociceptive and anti-allergy activities of patchouli oil. The antinociceptive activity of patchouli oil (20, 40, and 80 mg/kg) was evaluated using the acetic acid-induced writhing test (NIH mice) and the hot-plate test (NIH mice), and those for anti-allergy activity were tested using Schultz–Dale reaction, the passive cutaneous anaphylaxis (PCA) test, and delayed-type hypersensitivity (DTH) test. All doses of patchouli oil could significantly (p
ISSN:2163-8152
1041-2905
2163-8152
DOI:10.1080/10412905.2013.809319