serological response of working farm dogs to a vaccine containing Leptospira interrogans serovars Copenhageni and Pomona, and L. borgpetersenii serovar Hardjo

AIMS: To evaluate the serological response in dogs to a commercial vaccine for use in cattle containing cultured strains of Leptospira interrogans serovars Copenhageni and Pomona, and L. borgpetersenii serovar Hardjo. METHODS: Blood samples were obtained from 67 working farm dogs on 12 farms, and th...

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Bibliographic Details
Published in:New Zealand veterinary journal 2014-03, Vol.62 (2), p.87-90
Main Authors: Cave, NJ, Harland, AL, Allott, SK
Format: Article
Language:English
Subjects:
agglutination tests
Animals
antibodies
Antibodies, Bacterial - blood
Bacterial Vaccines - immunology
blood
cattle
Copenhageni
dog
Dog Diseases - prevention & control
Dogs
farms
Hardjo
Immunology
Leptospira - classification
Leptospira - immunology
Leptospira interrogans
Leptospirosis
Leptospirosis - prevention & control
Leptospirosis - veterinary
Pomona
Serologic Tests
seroprevalence
serotypes
vaccination
vaccine
Vaccines
Working dogs
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Summary:AIMS: To evaluate the serological response in dogs to a commercial vaccine for use in cattle containing cultured strains of Leptospira interrogans serovars Copenhageni and Pomona, and L. borgpetersenii serovar Hardjo. METHODS: Blood samples were obtained from 67 working farm dogs on 12 farms, and the microscopic agglutination test (MAT) was used to measure titres to the Leptospira spp. serovars Pomona, Hardjo, and Copenhageni. Samples with a titre of 100; for serovar Hardjo, 19/20 (95%) dogs had titres, with 18/20 (90%) being >100; and for serovar Copenhageni, 15/17 (88%) dogs that were initially seronegative had titres, with 6/17 (35%) being >100. The median titres for Pomona and Hardjo (200 (95% CI=179–359) and 200 (95% CI=176–379), respectively) were lower than for Copenhageni (50 (95% CI=26–124)) in dogs originally seronegative (p
ISSN:1176-0710
0048-0169
1176-0710
DOI:10.1080/00480169.2013.845072