Effects of tamoxifen on periodontal disease and

is involved in periodontal disease, which is influenced by sex hormones. To study the effects of the estrogen antagonist tamoxifen (TAM) on periodontal disease of oncological patients; clinical oral strains of . With periodontitis and breast cancer and other with AIDS were used. Periodontal disease...

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Bibliographic Details
Published in:Future microbiology 2019-01, Vol.14 (2), p.129-137
Main Authors: Muthular, Milagros, Bálsamo, Fernanda, Passero, Pablo, Jewtuchowicz, Virginia, Miozza, Valeria, Villalba, Marcelo Blanco, Brusca, María Isabel, Pérez, Cristina
Format: Article
Language:English
Subjects:
antifungal
antitumoral
azoles
breast cancer
immunocompromise
periodontal disease
resistance
tamoxifen
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Summary:is involved in periodontal disease, which is influenced by sex hormones. To study the effects of the estrogen antagonist tamoxifen (TAM) on periodontal disease of oncological patients; clinical oral strains of . With periodontitis and breast cancer and other with AIDS were used. Periodontal disease was evaluated by the academy of periodontology procedures and the growth of clinical isolates were evaluated by the Clinical and Laboratory Standards Institute techniques. Women who consumed TAM for more than 2 years decreased periodontitis severity. , TAM inhibited the growth of both fluconazole-sensitive and resistant . Administered TAM chronically improves periodontal health and has antifungal activity on oral strains isolated from patients with odontologic and medical pathologies.
ISSN:1746-0913
1746-0921
DOI:10.2217/fmb-2018-0272