Nucleic acid detection in the diagnosis and prevention of schistosomiasis

Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites a...

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Bibliographic Details
Published in:Infectious diseases of poverty 2016-03, Vol.5 (25)
Main Authors: Wu, Zhong-dao, Song, Lan-gui, Liang, Jin-yi, He, Ping, Lv, Zhi-yue, Xie, Hui, Yuan, Dong-ya
Format: Article
Language:English
Subjects:
Diagnosis
Genetic aspects
Identification and classification
Innovations
Molecular diagnostic techniques
Nucleic acids
Schistosomiasis
Online Access:Get full text
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Summary:Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites are increasing, novel techniques for detection incorporating nucleotide sequences are receiving widespread attention. These sensitive, specific, and rapid detection methods are particularly important in the diagnosis of low-grade and early infections, and may prove to have clinical significance. This paper reviews the progress of nucleic acid detection in the diagnosis and prevention of schistosomiasis, including such aspects as the selection of target genes, and development and application of nucleic acid detection methods. Keywords: Schistosoma japonicum , S. mansoni , S. haematobium , Diagnosis, Nucleic acid detection
ISSN:2049-9957
2049-9957