Quality of life in overweight

Objective: Polycystic ovary syndrome (PCOS) is characterized by phenotypic heterogeneity and has a wide variety of consequences. Approximately half of women with PCOS are overweight or obese, and their obesity may be a contributing factor to PCOS pathogenesis through different mechanisms. The aim of...

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Published in:Patient preference and adherence 2020-03, p.423
Main Authors: Cacciapuoti, Marianna, Lupoli, Roberta, Valenzano, Anna, Monda, Marcellino, Lupoli, Giovanni, Panico, Annalisa, Gelsy Lupoli, Arianna, Precenzano, Francesco, Messina, Antonietta, Cibelli, Giuseppe, Monda, Vincenzo, Messina, Giovanni, Villano, Ines, Moscatelli, Fiorenzo, Esposito, Teresa
Format: Article
Language:English
Subjects:
Analysis
Body mass index
Diseases
Health
Health surveys
Obesity
Polycystic ovary syndrome
Stress (Psychology)
Women's health
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Summary:Objective: Polycystic ovary syndrome (PCOS) is characterized by phenotypic heterogeneity and has a wide variety of consequences. Approximately half of women with PCOS are overweight or obese, and their obesity may be a contributing factor to PCOS pathogenesis through different mechanisms. The aim of this study was to evaluate if PCOS alone affects the patients' quality of life and to what extent obesity contributes to worsen this disease. Design: To evaluate the impact of PCOS on health-related quality-of-life (HRQoL), 100 Mediterranean women with PCOS (group A), 50 with a body mass index (BMI) >25 kg/[m.sup.2] (group [A.sub.1]) and 50 with BMI 25 ([A.sub.1]) showed a significant and more marked reduction in scores, suggesting a lower quality of life, compared with controls (B) and with normal-weight PCOS patients ([A.sub.2]). Conclusion: PCOS is a complex disease that alone determines a deterioration of HRQoL. The innovative use of these psychometric questionnaires in this study, in particular the PCOS questionnaire, has highlighted that obesity has a negative effect on HRQoL. It follows that a weight decrease is associated to phenotypic spectrum improvement and relative decrement in psychological distress. Keywords: polycystic ovary syndrome, obesity, normal-weight, health-related quality-of-life, psychological disturbances
ISSN:1177-889X
1177-889X