Lack of coordination between partners: investigation of Physician-Preferred and Patient-Preferred

• Published in: Patient preference and adherence 2020-03, p.1253
• Main Authors: Wang, Yunlin, He, Ling, Chen, Chen,Bo, Li, Xiaowei, Zhao, Yunjuan, Zhang, Xiaodan, Du, Tao, Zhang, Tong, Li, Wangen, Liu, Ruike
• Format: Article
• Language: English
• Subjects: Algorithms; Blood glucose; Clinical trials; Decision making; Glucose; Hypoglycemic agents; Insulin; Insulin glargine; Patient care; Type 2 diabetes
• ISSN: 1177-889X; 1177-889X

Background: Patient-centered care is respectful to a patient's preference. All prior clinical trials on patient self-titration algorithms for basal insulin were decided by physicians. We hypothesized that patients and physicians have different preferences. Patients and methods: Physicians and diabetes patients were asked to choose their preferred insulin glargine self-titration algorithm among 5 algorithms. Algorithm 1, 1 U increase once daily; algorithm 2, 2 U increase every 3 days; algorithm 3, 3 U increase every 3 days; algorithm 4, titration every 3 days according to fasting blood glucose, and algorithm 5, weekly titration 2-8 U based on 3-day mean fasting blood glucose levels. Results: Eleven (5.2%) out of 210 physicians and 180 (90.9%) out of 198 patients preferred algorithm 1 ([chi square]=300.4, p=0.000). In contrast, 195 (92.9%) physicians and 18 (9.1%) patients preferred algorithm 2 ([chi square]=286.6, p=0.000). In addition, 4 (1.9%) physicians but no patients preferred algorithm 3 ([chi square]=2.099, p=0.124). Neither physicians nor patients chose algorithms 4 or 5. Most physicians preferred algorithm 2 since it is recommended by guidelines, but most patients preferred algorithm 1 for its simplicity. Conclusion: Patients had different preferences compared with physicians. Attention should be given to patients' preferences to increase adherence and improve glycemic control. Keywords: type 2 diabetes, titration algorithm, insulin glargine, basal insulin, self-adjustment, shared decision-making, adherence