Chronic Obstructive Pulmonary Disease

Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we invest...

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Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease 2021-05, Vol.16, p.1353
Main Authors: Shapkina, Marina, Hopstock, Laila A, Kudryavtsev, Alexander V, Quint, Jennifer K, Malyutina, Sofia, Eggen, Anne Elise, Cook, Sarah, Melbye, Hasse
Format: Article
Language:English
Subjects:
Analysis
Health aspects
Lung diseases, Obstructive
Medical research
Medicine, Experimental
Mortality
Norway
Prevalence studies (Epidemiology)
Russia
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Summary:Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based study conducted in two Russian cities and compared the findings with a similar study from Norway conducted in the same time period. Methods: The study population was a sub-sample of participants aged 40-69 years participating in the Know Your Heart (KYH) study in Russia in 2015-18 (n=1883) and in the 7th survey of the Tromso Study (n=5271) carried out in Norway in 2015-16 (Tromso 7) who participated in spirometry examinations. The main outcome was obstructive lung function (FEVi/FVC ratio< lower limit of normal on pre-bronchodilator spirometry examination) with and without respiratory symptoms (chronic cough and breathlessness). In those with obstructive lung function, awareness (known diagnosis) and management (use of medications, smoking cessation) were compared. Results: The age-standardized prevalence of obstructive lung function was similar among men in both studies (KYH 11.0% vs Tromso 7 9.8%, p=0.21) and higher in the Norwegian (9.4%) than Russian (6.8%) women (p=0.006). In contrast, the prevalence of obstructive lung function plus respiratory symptoms was higher in Russian men (KYH 8.3% vs Tromso 7 4.7%, p
ISSN:1178-2005