The Elusive SLIPPERS Syndrome

Background: In 2015, the term "SLIPPERS" was created to refer to a rare type of encephalomyelitis called CLIPPERS syndrome that affects the pons and sometimes other nearby structures, but in this case, it primarily affects the supratentorial region. This variation of the condition is respo...

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Bibliographic Details
Published in:International medical case reports journal 2023-06, Vol.16, p.357
Main Authors: Baregzai, Younis, Hammadi, Firas, Khan, Adnan, Ibrahim, Wanis, Khan, Muhammad Mohsin, Bozom, Issam A. Al
Format: Article
Language:English
Subjects:
B cells
Care and treatment
Seizures (Medicine)
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Summary:Background: In 2015, the term "SLIPPERS" was created to refer to a rare type of encephalomyelitis called CLIPPERS syndrome that affects the pons and sometimes other nearby structures, but in this case, it primarily affects the supratentorial region. This variation of the condition is responsive to treatment with steroids. Case Description: We report the case of a patient who presented with seizures and visual field deficit and had typical radiological and histopathological characteristics of SLIPPERS syndrome. Conclusion: Although the literature is inundated with CLIPPERS syndrome, its supratentorial variant is extremely rare. To our knowledge, this is fourth case of SLIPPERS syndrome to be reported in literature and serves to enhance clinicopathological understanding of this elusive entity. Keywords: CLIPPERS, SLIPPERS, corticosteroids, neuroinflammation, perivascular infiltration
ISSN:1179-142X
1179-142X