Inhibiting glycolytic metabolism enhances [CD8.sup.+] T cell memory and antitumor function

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Bibliographic Details
Published in:Journal of Clinical Investigation 2013, Vol.123 (10), p.4479
Main Authors: Sukumar, Madhusudhanan, Liu, Jie, Ji, Yun, Subramanian, Murugan, Crompton, Joseph G, Yu, Zhiya, Roychoudhuri, Rahul, Palmer, Douglas C, Muranski, Pawel, Karoly, Edward D, Mohney, Robert P, Klebanoff, Christopher A, Lal, Ashish, Finkel, Toren, Restifo, Nicholas P, Gattinoni, Luca
Format: Report
Language:English
Subjects:
CD8 lymphocytes
Cellular control mechanisms
Cellular therapy
Glucose metabolism
Observations
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ISSN:0021-9738
DOI:10.1172/JCI69589