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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease

Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses.

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Published in:Journal of Clinical Investigation 2022, Vol.132 (12)
Main Authors: Dwyer, Gaelen K, Mathews, Lisa R, Villegas, Jose A, Lucas, Anna, de Peredo, Anne Gonzalez, Blazar, Bruce R, Girard, Jean-Philippe, Poholek, Amanda C, Luther, Sanjiv A, Shlomchik, Warren, Turnquist, Heth R
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container_issue 12
container_start_page
container_title Journal of Clinical Investigation
container_volume 132
creator Dwyer, Gaelen K
Mathews, Lisa R
Villegas, Jose A
Lucas, Anna
de Peredo, Anne Gonzalez
Blazar, Bruce R
Girard, Jean-Philippe
Poholek, Amanda C
Luther, Sanjiv A
Shlomchik, Warren
Turnquist, Heth R
description Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses.
doi_str_mv 10.1172/JCI150927
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identifier ISSN: 0021-9738
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source PubMed (Medline); EZB Electronic Journals Library
subjects Antigen presenting cells
Care and treatment
Cellular signal transduction
Development and progression
Graft versus host reaction
Health aspects
Hematopoietic stem cells
Immunological research
Interleukins
Physiological aspects
Stem cells
T cells
Transplantation
title IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
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