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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses.
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Published in: | Journal of Clinical Investigation 2022, Vol.132 (12) |
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Main Authors: | , , , , , , , , , , |
Format: | Report |
Language: | English |
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container_issue | 12 |
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container_title | Journal of Clinical Investigation |
container_volume | 132 |
creator | Dwyer, Gaelen K Mathews, Lisa R Villegas, Jose A Lucas, Anna de Peredo, Anne Gonzalez Blazar, Bruce R Girard, Jean-Philippe Poholek, Amanda C Luther, Sanjiv A Shlomchik, Warren Turnquist, Heth R |
description | Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses. |
doi_str_mv | 10.1172/JCI150927 |
format | report |
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Lucas, Anna ; de Peredo, Anne Gonzalez ; Blazar, Bruce R ; Girard, Jean-Philippe ; Poholek, Amanda C ; Luther, Sanjiv A ; Shlomchik, Warren ; Turnquist, Heth R</creator><creatorcontrib>Dwyer, Gaelen K ; Mathews, Lisa R ; Villegas, Jose A ; Lucas, Anna ; de Peredo, Anne Gonzalez ; Blazar, Bruce R ; Girard, Jean-Philippe ; Poholek, Amanda C ; Luther, Sanjiv A ; Shlomchik, Warren ; Turnquist, Heth R</creatorcontrib><description>Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses.</description><identifier>ISSN: 0021-9738</identifier><identifier>DOI: 10.1172/JCI150927</identifier><language>eng</language><publisher>American Society for Clinical Investigation</publisher><subject>Antigen presenting cells ; Care and treatment ; Cellular signal transduction ; Development and progression ; Graft versus host reaction ; Health aspects ; Hematopoietic stem cells ; Immunological research ; Interleukins ; Physiological aspects ; Stem cells ; 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fulltext | fulltext |
identifier | ISSN: 0021-9738 |
ispartof | Journal of Clinical Investigation, 2022, Vol.132 (12) |
issn | 0021-9738 |
language | eng |
recordid | cdi_gale_incontextgauss_IOV_A708110375 |
source | PubMed (Medline); EZB Electronic Journals Library |
subjects | Antigen presenting cells Care and treatment Cellular signal transduction Development and progression Graft versus host reaction Health aspects Hematopoietic stem cells Immunological research Interleukins Physiological aspects Stem cells T cells Transplantation |
title | IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease |
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