Acetylcholine-Induced Ca2+ Flux across the Sarcolemma of an Echinoderm Smooth Muscle

A study has been conducted to examine the effect of acetylcholine on calcium flow across the sarcolemma of sea cucumber, Sclerodactyla briareus, using the calcium-selective electrode technique. The results showed that acetylcholine causes excitation of the membrane that promotes calcium release from...

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Bibliographic Details
Published in:The Biological bulletin (Lancaster) 1995-10, Vol.189 (2), p.207-207
Main Authors: Devlin, C. L., Smith, P. J. S.
Format: Article
Language:English
Subjects:
Acetylcholine
Calcium channels
Holothurians
Physiological aspects
Sarcolemma
Sea cucumbers
Online Access:Get full text
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Summary:A study has been conducted to examine the effect of acetylcholine on calcium flow across the sarcolemma of sea cucumber, Sclerodactyla briareus, using the calcium-selective electrode technique. The results showed that acetylcholine causes excitation of the membrane that promotes calcium release from the elongated subsarcolemmal sacs. Application of agents that could alter the normal activity of the sodium-calcium channel showed that sodium ions are necessary in stimulating calcium mobilization through the voltage-gated channels from an intracellular source.
ISSN:0006-3185
1939-8697
DOI:10.1086/BBLv189n2p207