Urinary and sexual outcomes in long-term

• Published in: Health and quality of life outcomes 2009-11, Vol.7, p.94
• Main Authors: Gacci, Mauro, Simonato, Alchiede, Masieri, Lorenzo, Gore, John L, Lanciotti, Michele, Mantella, Annalisa, Rossetti, Mario Alberto, Serni, Sergio, Varca, Virginia, Romagnoli, Andrea, Ambruosi, Carlo, Venzano, Fabio, Esposito, Marco, Montanaro, Tomaso, Carmignani, Giorgio, Carini, Marco
• Format: Article
• Language: English
• Subjects: Care and treatment; Health aspects; Patient outcomes; Prostate cancer; Prostatectomy; Risk factors; Urinary incontinence
• ISSN: 1477-7525; 1477-7525
• DOI: 10.1186/1477-7525-7-94

After long term disease free follow up (FUp) patients reconsider quality of life (QOL) outcomes. Aim of this study is assess QoL in prostate cancer patients who are disease-free at least 5 years after radical prostatectomy (RP). 367 patients treated with RP for clinically localized pCa, without biochemical failure (PSA [less than or equal to] 0.2 ng/mL) at the follow up [greater than or equal to] 5 years were recruited. Time since prostatectomy had a negative effect on SF and a positive effect SB (both p [less than] 0.001). Elderly men at follow up experienced worse UF and SF (p = 0.02 and p [less than] 0.001) and better SB (p [less than] 0.001). Older age at follow up and higher pathological stage were associated with worse QoL outcomes after RP. The direct correlation between UF and age at follow up, with no correlation between UF and age at time of RP suggests that other issues (i.e: vascular or neurogenic disorders), subsequent to RP, are determinant on urinary incontinence. After NS-RP without HT the correlation between SF and SB is maintained for 7 years, after which function and bother appear to have divergent trajectories.