Development and validation of quick Acute Kidney Injury-score

AKI is associated with increased risk of death, prolonged length of stay and development of de-novo chronic kidney disease. The aim of our study is the development and validation of prediction models to identify the risk of AKI in ICU patients up to 7 days. We retrospectively recruited 692 consecuti...

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Bibliographic Details
Published in:PloS one 2019-06, Vol.14 (6), p.e0217424
Main Authors: Ferrari, Fiorenza, Puci, Mariangela Valentina, Ferraro, Ottavia Eleonora, Romero-González, Gregorio, Husain-Syed, Faeq, Rizo-Topete, Lilia, Senzolo, Mara, Lorenzin, Anna, Muraro, Eva, Baracca, Antonio, Serrano-Soto, Mara, Molano Triviño, Alejandra, Coutinho Castro, Ana, De Cal, Massimo, Corradi, Valentina, Brendolan, Alessandra, Scarpa, Marta, Carta, Maria Rosa, Giavarina, Davide, Bonato, Raffaele, Iotti, Giorgio Antonio, Ronco, Claudio
Format: Article
Language:English
Subjects:
Acute kidney failure
Analysis
Care and treatment
Chronic kidney failure
Critically ill persons
Death
Health aspects
Hospital patients
Intensive care units
Kidney diseases
Lactates
Medical research
Patient outcomes
Practice guidelines (Medicine)
Risk factors
Services
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Summary:AKI is associated with increased risk of death, prolonged length of stay and development of de-novo chronic kidney disease. The aim of our study is the development and validation of prediction models to identify the risk of AKI in ICU patients up to 7 days. We retrospectively recruited 692 consecutive patients admitted to the ICU at San Bortolo Hospital (Vicenza, Italy) from 1 June 2016 to 31 March 2017: 455 patients were treated as the derivation group and 237 as the validation group. Candidate variables were selected based on a literature review and expert opinion. Admission eGFR< 90 ml/min /1.73 mq (OR 2.78; 95% CI 1.78-4.35; p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0217424