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The association of sun exposure, ultraviolet radiation effects and other risk factors for pterygium
To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. A population-based, cross-sectional multicentric study was conducted in adults aged [greater than or equal to]40 years in plains, hilly and coastal regions of India. All participants underwent a de...
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Published in: | PloS one 2022-07, Vol.17 (7) |
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creator | Tandon, Radhika Vashist, Praveen Gupta, Noopur Gupta, Vivek Yadav, Saumya Deka, Dipali Singh, Sachchidanand Vishwanath, K Murthy, G. V. S |
description | To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. A population-based, cross-sectional multicentric study was conducted in adults aged [greater than or equal to]40 years in plains, hilly and coastal regions of India. All participants underwent a detailed questionnaire-based assessment for sun exposure, usage of sun protective measures, exposure to indoor smoke, and smoking. Detailed ocular and systemic examinations were performed. Pterygium was diagnosed and graded clinically by slit-lamp examination. Association of pterygium with sociodemographic, ophthalmological, and systemic parameters was assessed. Physical environmental parameters for the study period were estimated. Of the 12,021 eligible subjects, 9735 (81% response rate) participated in the study. The prevalence of pterygium in any eye was 13.2% (95% CI: 12.5%-13.9%), and bilateral pterygium was 6.7% (95% CI: 6.2-7.2). The prevalence increased with age ( |
doi_str_mv | 10.1371/journal.pone.0270065 |
format | article |
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V. S</creator><creatorcontrib>Tandon, Radhika ; Vashist, Praveen ; Gupta, Noopur ; Gupta, Vivek ; Yadav, Saumya ; Deka, Dipali ; Singh, Sachchidanand ; Vishwanath, K ; Murthy, G. V. S</creatorcontrib><description>To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. A population-based, cross-sectional multicentric study was conducted in adults aged [greater than or equal to]40 years in plains, hilly and coastal regions of India. All participants underwent a detailed questionnaire-based assessment for sun exposure, usage of sun protective measures, exposure to indoor smoke, and smoking. Detailed ocular and systemic examinations were performed. Pterygium was diagnosed and graded clinically by slit-lamp examination. Association of pterygium with sociodemographic, ophthalmological, and systemic parameters was assessed. Physical environmental parameters for the study period were estimated. Of the 12,021 eligible subjects, 9735 (81% response rate) participated in the study. The prevalence of pterygium in any eye was 13.2% (95% CI: 12.5%-13.9%), and bilateral pterygium was 6.7% (95% CI: 6.2-7.2). The prevalence increased with age (<0.001) irrespective of sex and was highest in those aged 60-69 years (15.8%). The prevalence was highest in coastal (20.3%), followed by plains (11.2%) and hilly regions (9.1%). On multi-logistic regression, pterygium was positively associated with coastal location (P<0.001), illiteracy (P = 0.037), increasing lifetime sun exposure (P<0.001), and negatively associated with BMI [greater than or equal to]25 kg/m2 (P = 0.009). Pterygium prevalence is high in the rural Indian population. The association of pterygium with several potentially modifiable risk factors reflects its multifactorial etiology and provides targets for preventive measures.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0270065</identifier><language>eng</language><publisher>Public Library of Science</publisher><subject>Daylight ; Health aspects ; Rural population ; Statistics ; Sunshine ; Ultraviolet radiation</subject><ispartof>PloS one, 2022-07, Vol.17 (7)</ispartof><rights>COPYRIGHT 2022 Public Library of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Tandon, Radhika</creatorcontrib><creatorcontrib>Vashist, Praveen</creatorcontrib><creatorcontrib>Gupta, Noopur</creatorcontrib><creatorcontrib>Gupta, Vivek</creatorcontrib><creatorcontrib>Yadav, Saumya</creatorcontrib><creatorcontrib>Deka, Dipali</creatorcontrib><creatorcontrib>Singh, Sachchidanand</creatorcontrib><creatorcontrib>Vishwanath, K</creatorcontrib><creatorcontrib>Murthy, G. V. S</creatorcontrib><title>The association of sun exposure, ultraviolet radiation effects and other risk factors for pterygium</title><title>PloS one</title><description>To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. A population-based, cross-sectional multicentric study was conducted in adults aged [greater than or equal to]40 years in plains, hilly and coastal regions of India. All participants underwent a detailed questionnaire-based assessment for sun exposure, usage of sun protective measures, exposure to indoor smoke, and smoking. Detailed ocular and systemic examinations were performed. Pterygium was diagnosed and graded clinically by slit-lamp examination. Association of pterygium with sociodemographic, ophthalmological, and systemic parameters was assessed. Physical environmental parameters for the study period were estimated. Of the 12,021 eligible subjects, 9735 (81% response rate) participated in the study. The prevalence of pterygium in any eye was 13.2% (95% CI: 12.5%-13.9%), and bilateral pterygium was 6.7% (95% CI: 6.2-7.2). The prevalence increased with age (<0.001) irrespective of sex and was highest in those aged 60-69 years (15.8%). The prevalence was highest in coastal (20.3%), followed by plains (11.2%) and hilly regions (9.1%). On multi-logistic regression, pterygium was positively associated with coastal location (P<0.001), illiteracy (P = 0.037), increasing lifetime sun exposure (P<0.001), and negatively associated with BMI [greater than or equal to]25 kg/m2 (P = 0.009). Pterygium prevalence is high in the rural Indian population. The association of pterygium with several potentially modifiable risk factors reflects its multifactorial etiology and provides targets for preventive measures.</description><subject>Daylight</subject><subject>Health aspects</subject><subject>Rural population</subject><subject>Statistics</subject><subject>Sunshine</subject><subject>Ultraviolet radiation</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqF0MtKAzEYBeAgCtbqG7jIShCcmkwyk8yyFC8FoaDFbUmTPzNTx6TkIvXtVeyirlyds_g4i4PQJSUTygS93fgcnBomW-9gQkpBSF0doRFtWFnUJWHHB_0UncW4IaRisq5HSC87wCpGr3uVeu-wtzhmh2G39TEHuMF5SEF99H6AhIMyewbWgk4RK2ewTx0EHPr4hq3SyYeIrQ94myB8tn1-P0cnVg0RLvY5Rsv7u-XssXhaPMxn06eibRpZMFtJSmvg1BCphagNMZbJChQvgYM2nEpVMqh4I2ip-FoTRtkaYN1oLQxnY3T9O9uqAVa9094l2KVW5RhX85fn1VRQSr7_quQ_dvH6114d2A7UkLroh_zzQzyEX4UCeEo</recordid><startdate>20220721</startdate><enddate>20220721</enddate><creator>Tandon, Radhika</creator><creator>Vashist, Praveen</creator><creator>Gupta, Noopur</creator><creator>Gupta, Vivek</creator><creator>Yadav, Saumya</creator><creator>Deka, Dipali</creator><creator>Singh, Sachchidanand</creator><creator>Vishwanath, K</creator><creator>Murthy, G. 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S</creatorcontrib><collection>Gale_Opposing Viewpoints In Context</collection><collection>Gale In Context: Science</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tandon, Radhika</au><au>Vashist, Praveen</au><au>Gupta, Noopur</au><au>Gupta, Vivek</au><au>Yadav, Saumya</au><au>Deka, Dipali</au><au>Singh, Sachchidanand</au><au>Vishwanath, K</au><au>Murthy, G. V. S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The association of sun exposure, ultraviolet radiation effects and other risk factors for pterygium</atitle><jtitle>PloS one</jtitle><date>2022-07-21</date><risdate>2022</risdate><volume>17</volume><issue>7</issue><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. A population-based, cross-sectional multicentric study was conducted in adults aged [greater than or equal to]40 years in plains, hilly and coastal regions of India. All participants underwent a detailed questionnaire-based assessment for sun exposure, usage of sun protective measures, exposure to indoor smoke, and smoking. Detailed ocular and systemic examinations were performed. Pterygium was diagnosed and graded clinically by slit-lamp examination. Association of pterygium with sociodemographic, ophthalmological, and systemic parameters was assessed. Physical environmental parameters for the study period were estimated. Of the 12,021 eligible subjects, 9735 (81% response rate) participated in the study. The prevalence of pterygium in any eye was 13.2% (95% CI: 12.5%-13.9%), and bilateral pterygium was 6.7% (95% CI: 6.2-7.2). The prevalence increased with age (<0.001) irrespective of sex and was highest in those aged 60-69 years (15.8%). The prevalence was highest in coastal (20.3%), followed by plains (11.2%) and hilly regions (9.1%). On multi-logistic regression, pterygium was positively associated with coastal location (P<0.001), illiteracy (P = 0.037), increasing lifetime sun exposure (P<0.001), and negatively associated with BMI [greater than or equal to]25 kg/m2 (P = 0.009). Pterygium prevalence is high in the rural Indian population. The association of pterygium with several potentially modifiable risk factors reflects its multifactorial etiology and provides targets for preventive measures.</abstract><pub>Public Library of Science</pub><doi>10.1371/journal.pone.0270065</doi></addata></record> |
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subjects | Daylight Health aspects Rural population Statistics Sunshine Ultraviolet radiation |
title | The association of sun exposure, ultraviolet radiation effects and other risk factors for pterygium |
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