Understanding Reproductive Health among Survivors of Paediatric and Young adults

Although reproductive failure after cancer treatment in children and young adults has been extensively described in high-income countries, there is a paucity of data in low-income settings. In addition, patient, parent, or health worker experiences, perspectives, and attitudes toward the risk of rep...

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Bibliographic Details
Published in:PloS one 2023-04, Vol.18 (4), p.e0284969
Main Authors: Kayiira, Anthony, Zaake, Daniel, Xiong, Serena, Balagadde, Joyce K, Ghebre, Rahel, Wabinga, Henry
Format: Article
Language:English
Subjects:
Cancer
Cancer in children
Cancer survivors
Care and treatment
Diagnosis
Health aspects
Management
Methods
Oncology, Experimental
Pediatrics
Reproductive health
Teenagers
Youth
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Summary:Although reproductive failure after cancer treatment in children and young adults has been extensively described in high-income countries, there is a paucity of data in low-income settings. In addition, patient, parent, or health worker experiences, perspectives, and attitudes toward the risk of reproductive failure among young cancer patients in these settings are unknown. This study will describe the extent of reproductive morbidity associated with cancer treatment among childhood and young adult cancer survivors in Uganda. In addition, we aim to explore the contextual enablers and barriers to addressing cancer treatment-related reproductive morbidity in Uganda. This is an explanatory sequential mixed-method study. The quantitative phase will be a survey among childhood and young adult cancer survivors recruited from the Kampala Cancer Registry (KCR). The survey will utilize a Computer Assisted Telephone Interview (CATI) platform on a minimum of 362 survivors. The survey will obtain information on self-reported reproductive morbidity and access to oncofertility care. The qualitative phase will use grounded theory to explore contextual barriers and enablers to addressing reproductive morbidity associated with cancer treatment. The quantitative and qualitative phases will be integrated at the intermediate and results stage.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0284969