Life-Threatening Complications of HIV Infection

Few modern diseases have experienced as rapid and dramatic change in prognosis and treatment as HIV infection. The introduction of active antiretroviral therapy (ART) and effective prophylaxis of opportunistic infections ushered in a new era in the treatment of HIV infection and changed dramatically...

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Bibliographic Details
Published in:Journal of intensive care medicine 2007-03, Vol.22 (2), p.73-81
Main Authors: Davaro, Raul E., Thirumalai, Annetha
Format: Article
Language:English
Subjects:
AIDS (Disease)
AIDS-Related Opportunistic Infections - diagnosis
AIDS-Related Opportunistic Infections - drug therapy
AIDS-Related Opportunistic Infections - physiopathology
Anti-Bacterial Agents - therapeutic use
Antiretroviral Therapy, Highly Active - adverse effects
Antiviral agents
Care and treatment
Highly active antiretroviral therapy
HIV infection
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - mortality
Hospital Mortality
Humans
Intensive Care Units - statistics & numerical data
Pneumonia, Pneumocystis - diagnosis
Pneumonia, Pneumocystis - drug therapy
Pneumonia, Pneumocystis - physiopathology
Prognosis
Toxoplasmosis, Cerebral - diagnosis
Toxoplasmosis, Cerebral - drug therapy
Toxoplasmosis, Cerebral - physiopathology
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Summary:Few modern diseases have experienced as rapid and dramatic change in prognosis and treatment as HIV infection. The introduction of active antiretroviral therapy (ART) and effective prophylaxis of opportunistic infections ushered in a new era in the treatment of HIV infection and changed dramatically the natural history of this disease. The rates of admission to the intensive care unit (ICU) and intensive care mortality in patients with HIV infection have shifted repeatedly during the AIDS epidemic, influenced by attitudes of patients and providers toward utility of care. In the ART era, patients with HIV infection admitted to the ICU fall into 3 general categories: those with AIDS-related opportunistic infections, those who are experiencing complications related to ART, and those with medical problems unrelated to HIV infection. In this article, the authors provide a review of the most common life-threatening complications in patients with HIV infection.
ISSN:0885-0666
1525-1489
DOI:10.1177/0885066606297964