Associations between melanocortin, dopamine and serotonin neurotransmission and physical activity

Regular physical exercise is beneficial for health. Despite well-known indications to maintain moderate physical activity (PA) throughout the lifetime, recommendations to stay active are disregarded by the majority of people. Brain neurotransmitter systems influence our motivation and reward. Animal...

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Bibliographic Details
Published in:Medicina Sportiva 2012, Vol.16 (1), p.40
Main Authors: Jozkow, Pawel, Slowinska-Lisowska, Malgorzata, Laczmanski, Lukasz, Medras, Marek
Format: Report
Language:English
Subjects:
Dopamine
Exercise
Genetic aspects
Neuropeptides
Physiological aspects
Serotonin
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Summary:Regular physical exercise is beneficial for health. Despite well-known indications to maintain moderate physical activity (PA) throughout the lifetime, recommendations to stay active are disregarded by the majority of people. Brain neurotransmitter systems influence our motivation and reward. Animal and human studies suggest that dopamine, melanocortin and serotonin may be involved in the regulation of PA. Interesting information has been revealed in association studies on the genes encoding the receptors of the above neuropeptides. Unfortunately, the complexity of interactions with the environment and differences in methods to assess PA do not allow easy conclusions. The area of the molecular basis of our lifestyle is yet to be explored.
ISSN:1429-0022
DOI:10.5604/17342260.987849