A new spirotryprostatin from the marine isolate of the fungus Aspergillus fumigatus

The new spirocyclic diketopiperazine alkaloid spirotryprostatin F was isolated from the marine isolate of the fungus Aspergillus fumigatus . The structure of the compound was established using on NMR spectroscopy, high-resolution mass spectrometry, and acid hydrolysis. Spirotryprostatin F in low and...

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Bibliographic Details
Published in:Chemistry of natural compounds 2012-03, Vol.48 (1), p.95-98
Main Authors: Afiyatullov, Sh. Sh, Zhuravleva, O. I., Chaikina, E. L., Anisimov, M. M.
Format: Article
Language:English
Subjects:
Fungi
Hydrolysis
Medicine
Nuclear magnetic resonance spectroscopy
Organic Chemistry
Pharmacy
Plant Sciences
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Summary:The new spirocyclic diketopiperazine alkaloid spirotryprostatin F was isolated from the marine isolate of the fungus Aspergillus fumigatus . The structure of the compound was established using on NMR spectroscopy, high-resolution mass spectrometry, and acid hydrolysis. Spirotryprostatin F in low and ultralow doses (10 –6 –10 –17  M) exhibited stimulating action on the growth of sprout roots of soy [ Glycine max (L.) Merr.], buckwheat ( Fagopyrum esculentum Moench), and corn ( Zea mays L.). The dose-effect curve had a bimodal character.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-012-0166-8