Synthesis and Cytotoxicity of Derivatives of Dipterocarpol, a Metabolite of Dipterocarpus alatus

New derivatives with hydroxy, epoxy, hydroxyimino, acetoxy, lactol, methoxylactol, and indole groups in ring A and the side chain were synthesized via chemical transformations of dipterocarpol. The structure– cytotoxicity relationship was described for the dipterocarpol derivatives.

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Bibliographic Details
Published in:Chemistry of natural compounds 2013-03, Vol.49 (1), p.58-65
Main Authors: Huong, Do Thi Thu, Thuy, Tran Thi Thu, Hien, Tran Thi, Tra, Nguyen Thanh, Tien, Nguyen Quyet, Smirnova, I. E., Kazakova, O. B., Minnibaeva, E. M., Tolstikov, G. A.
Format: Article
Language:English
Subjects:
Epoxy resins
Medicine
Metabolites
Organic Chemistry
Pharmacy
Plant Sciences
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Description
Summary:New derivatives with hydroxy, epoxy, hydroxyimino, acetoxy, lactol, methoxylactol, and indole groups in ring A and the side chain were synthesized via chemical transformations of dipterocarpol. The structure– cytotoxicity relationship was described for the dipterocarpol derivatives.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-013-0505-4