Optimization of the Extraction of Biologically Active Substances from Yellow Toadflax (Linaria vulgaris) Herb

Optimization of the extraction of biologically active substances from yellow toadflax produced data indicating that the active principles were extracted most completely from raw material if vacuum-filtration extraction was used. The process was carried out with heating at 42°C, infusion for 40 min,...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2014-07, Vol.48 (4), p.273-275
Main Authors: El’kina, O. V., Shramm, N. I., Molokhova, E. I., Petrichenko, V. M.
Format: Article
Language:English
Subjects:
Isoflavones
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Raw materials
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Summary:Optimization of the extraction of biologically active substances from yellow toadflax produced data indicating that the active principles were extracted most completely from raw material if vacuum-filtration extraction was used. The process was carried out with heating at 42°C, infusion for 40 min, and solid:liquid phase ratio 1:10. The yield of extracted flavonoids under these conditions was 96.7% of the total content in the raw material; of iridoids, 93.8%. The selected parameters could be considered optimal and recommended as industrial processing parameters for further production of extracts and their integration into medical practice.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-014-1092-9