Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation

Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2016-11, Vol.50 (8), p.537-542
Main Authors: Nifontova, G. O., Krechetov, S. P., Korostylev, E. V., Akhmetzyanova, A. R., Krasnyuk, I. I.
Format: Article
Language:English
Subjects:
Drug Synthesis Methods and Manufacturing Technology
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required amben release kinetics.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-016-1485-z